How Biological Technology Should Inform the Causal Selection Debate

How Clinical Development Can, and Should, Inform Translational Science

There is an urgent need for preclinical translational efforts to be realized as breakthroughs in therapy for the many patients with life-altering conditions affecting the CNS. Despite intensive efforts, few transformative therapies have emerged, and many new potential therapies that looked promising in preclinical development have failed in the clinic. In this Perspective, we suggest that if pr...

How the humanities inform medicine.

Nuclear Disarmament: Can Risk Analysis Inform the Debate?

This report is a preprint of a manuscript that has been submitted for possible journal publication. It should not be quoted or referenced without contacting the author to ensure it remains current. The author may be contacted at penelson@ne. The possibility of adapting risk analysis to events deemed to have infinite consequences is illustrated in the context of a simple dynamic two-event model....

How Should We Define Global Catastrophic Biological Risks?

The essay by the Johns Hopkins Center for Health Security on global catastrophic biological risks (GCBRs) presents an intriguing opportunity to assess the value of discriminating biologically derived risks from other global catastrophic risks (GCRs). Little research has focused on GCRs as a collective field of study, albeit individual types of GCRs have arguably received significant attention (...

Biological versus electronic adaptive coloration: how can one inform the other?

Adaptive reflective surfaces have been a challenge for both electronic paper (e-paper) and biological organisms. Multiple colours, contrast, polarization, reflectance, diffusivity and texture must all be controlled simultaneously without optical losses in order to fully replicate the appearance of natural surfaces and vividly communicate information. This review merges the frontiers of knowledg...